February 1, 2016

NRG Oncology funding depends on corresponding authors' compliance with NIH Manuscript Submission System (NIHMS) requirements. If authors do not comply, we will not receive our grant funds. If you are the corresponding author on a manuscript to be published under NRG auspices, please click here and note your responsibilities under the NIH Public Access policy.

AMENDMENTS AND UPDATES
HEAD & NECK
RTOG 1008: Study memorandum, February 1, 2016 (replaces January 25, 2016 memorandum).

LUNG
RTOG 0617: Amendment 12; Version Date: January 19, 2016; also available on the CTSU website.

OTHER PROTOCOL NOTICES
BREAST
NSABP-B-55/BIG-6-13: IDMC Meeting information for NSABP B-55/BIG 6-13 has been posted to CTSU.

Vision Tree Webinar
The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001 and NRG-HN002. Space is limited so register now and reserve your seat. The next webinar training is scheduled for February 17, 2016.

DRUG SAFETY UPDATES
Safety updates have been issued for GOG legacy studies. For details, please see the GOG Weekly Mailing page.

Safety updates have been issued for NSABP legacy studies. For details, please see the NSABP Members’ Area or the E-mail Distributions page and the CTSU website.

Safety updates have been issued for the following NRG Oncology studies:
Nivolumab: NRG-GY002, NRG-GY003, NRG-BN002
Ipilimumab: NRG-GY003, NRG-BN002
For NRG-GY002 and NRG-GY003 safety reports, please see the protocol page on the NRG Oncology website for details.
For NRG-BN002 safety reports, please see the RTOG General Broadcast page for details.

The NRG Oncology Biospecimen Bank- San Francisco will be closed Monday, February 15, 2016 in observance of the President’s Day Holiday. We will reopen on Tuesday the 16th.
The NRG Columbus and Pittsburgh banks are open for business as usual.
Please contact us at NRBBB@ucsf.edu or 415-476-7864 with any questions.

NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

JOURNAL ARTICLES
Dalerba P, Sahoo D, Paik S, Guo X, Yothers G, Song N, Wilcox-Fogel N, Forgó E, Rajendran PS, Miranda SP, Hisamori S, Hutchison J, Kalisky T, Qian D, Wolmark N, Fisher GA, van de Rijn M, Clarke MF. CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer. N Engl J Med. 2016 Jan 21;374(3):211-22. doi: 10.1056/NEJMoa1506597. PubMed PMID: 26789870. Read more
http://www.nejm.org/doi/pdf/10.1056/NEJMoa1506597

Robins HI, Zhang P, Gilbert MR, Chakravarti A, de Groot JF, Grimm SA, Wang F, Lieberman FS, Krauze A, Trotti AM, Mohile N, Kee AY, Colman H, Cavaliere R, Kesari S, Chmura SJ, Mehta M. A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study. J Neurooncol. 2016 Jan;126(2):309-16. doi: 10.1007/s11060-015-1966-z. Epub 2015 Oct 27. PubMed PMID: 26508094; PubMed Central PMCID: PMC4720526. Read more

Shah MA, Renfro LA, Allegra CJ, André T, de Gramont A, Schmoll HJ, Haller DG, Alberts SR, Yothers G, Sargent DJ. Impact of Patient Factors on Recurrence Risk and Time Dependency of Oxaliplatin Benefit in Patients with Colon Cancer: Analysis From Modern-Era Adjuvant Studies in the Adjuvant Colon Cancer End Points (ACCENT) Database. J Clin Oncol. 2016 Jan 25. pii: JCO630558. [Epub ahead of print] PubMed PMID: 26811529. Read more

Yothers G, Song N, George TJ Jr. Cancer Hallmark-Based Gene Sets and Personalized Medicine for Patients With Stage II Colon Cancer. JAMA Oncol. 2016 Jan 1;2(1):23-4. doi: 10.1001/ jamaoncol.2015.3614. PubMed PMID: 26501743. Read more

PUBLICATIONS REMINDERS
Please note the following upcoming meeting and abstract submission deadline dates.

Upcoming abstract submission deadlines
American Association of Physicists in Medicine (AAPM) Jul 31-Aug 4, 2016; Washington DC, due to publications committee Feb 25, 2016; meeting abstract submission deadline Mar 10, 2016.

American Society of Clinical Oncology (ASCO) Jun 3-7, 2016, Chicago, IL; meeting abstract submission deadline Feb 2, 2016.

American Society for Radiation Oncology (ASTRO) Sep 25-28, 2016, Boston, MA; due to publications committee Feb 3, 2016; meeting abstract submission deadline Feb 17, 2016.

College of American Pathologists (CAP),Sep 25–28, 2016;Las Vegas, NV, due to publications committee Feb 26, 2016; meeting abstract submission deadline Mar 11, 2016.

Multinational Association of Supportive Care in Cancer (MASCC), Jun 23-25, 2016, Adelaide, Australia; due to publications committee Feb 2, 2016; meeting abstract submission deadline Feb 16, 2016.

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