April 13, 2015

NRG-BN002: Will open to patient entry on April 16, 2015; Study Activation Memorandum

NRG-CC002: Amendment 1; version date: March 26, 2015. Non-English speaking patients may participate if there is a validated translation of the assessment available; clarifications to the eligibility, assessment and treatment plan sections; removal of information regarding the CIRB in Section 8.

NRG Oncology Biospecimen Bank - San Francisco has revised the Specimen Transmittal Form (ST Form).  Updates include biospecimen bank name, email and website. Please use the new version posted here

RTOG 1112: Please help us reach our goal to accrue 12 patients a month (RTOG non-Asian centers) and 17 patients a month (Including the Asian centers) to RTOG 1112: “Randomized Phase III Study of Sorafenib versus Stereotactic Body Radiation Therapy (SBRT) followed by Sorafenib in Hepatocellular Carcinoma (HCC)”

Recruitment and study materials can be found on both the CTSU and RTOG websites. 

Vision Tree Webinar
The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0938, 0924, and 0920. Space is limited so register now and reserve your seat. The next training is scheduled for April 21, 2015.


Safety updates and an Investigator’s Brochure update have been issued for GOG legacy studies.  For details, please see the GOG Weekly Mailing page.

Safety updates have been issued for NSABP legacy studies. For details, please see the NSABP Member's Area or the E-mail distributions page and the CTSU website.

Safety updates and an Investigator’s Brochure update have been issued for RTOG legacy studies. For details, please see the RTOG General Broadcast page.
The SOCRA exam will be available at the NRG Oncology Semiannual Meeting in July.

Exam Location: Sheraton Denver Hotel Downtown
Date/Time: July 16, 2015 - 9:00 a.m. - 1:00 p.m.
Application Deadline: 6/4/2015

Please visit the SOCRA website for registration and further information.

NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.


Bruner DW, Hunt D, Michalski JM, Bosch WR, Galvin JM, Amin M, Xiao C, Bahary JP, Patel M, Chafe S, Rodrigues G, Lau H, Duclos M, Baikadi M, Deshmukh S, Sandler HM.  Preliminary patient-reported outcomes analysis of 3-dimensional radiation therapy versus intensity-modulated radiation therapy on the high-dose arm of the Radiation Therapy Oncology Group (RTOG) 0126 prostate cancer trial.  Cancer. 2015 Apr 2. doi: 10.1002/cncr.29362. [Epub ahead of print] PubMed PMID: 25847819.  Read more

Coleman RL, Sill MW, Bell-McGuinn K, Aghajanian C, Gray HJ, Tewari KS, Rubin SC, Rutherford TJ, Chan JK, Chen A, Swisher EM.  A phase II evaluation of the potent, highly selective PARP inhibitor veliparib in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer in patients who carry a germline BRCA1 or BRCA2 mutation - An NRG Oncology/Gynecologic Oncology Group study.  Gynecol Oncol. 2015 Mar 24. pii:S0090-8258(15)00759-3. doi:10.1016/j.ygyno.2015.03.042. [Epub ahead of print]. PubMed PMID: 25818403.  Read more

Ling TC, Slater JM, Mifflin R, Nookala P, Grove R, Ly AM, Patyal B, Slater JD,Yang GY.  Evaluation of normal tissue exposure in patients receiving radiotherapy for pancreatic cancer based on RTOG 0848.  J Gastrointest Oncol. 2015 Apr;6(2):108-14. doi: 10.3978/j.issn.2078-6891.2014.094. PubMed PMID: 25830030; PMCID: PMC4311087.  Read more

Moore KL, Schmidt R, Moiseenko V, Olsen LA, Tan J, Xiao Y, Galvin J, Pugh S, Seider MJ, Dicker AP, Bosch W, Michalski J, Mutic S.  Quantifying Unnecessary Normal Tissue Complication Risks due to Suboptimal Planning: A Secondary Study of RTOG 0126.  Int J Radiat Oncol Biol Phys. 2015 Apr 3. pii: S0360-3016(15)00152-2.  doi: 10.1016/j.ijrobp.2015.01.046. [Epub ahead of print] PubMed PMID: 25847605.  Read more

Renfro LA, Grothey A, Kerr D, Haller DG, André T, Van Cutsem E, Saltz L, Labianca R, Loprinzi CL, Alberts SR, Schmoll H, Twelves C, Yothers G, Sargent DJ; Adjuvant Colon Cancer Endpoints (ACCENT) Group; Adjuvant Colon Cancer Endpoints ACCENT Group.  Survival following early-stage colon cancer: an ACCENT-based comparison of patients versus a matched international general population.  Ann Oncol. 2015 Feb 19. pii: mdv073. [Epub ahead of print] PubMed PMID: 25697217.  Read more

Viswanathan AN, Moughan J, Miller BE, Xiao Y, Jhingran A, Portelance L, Bosch WR, Matulonis UA, Horowitz NS, Mannel RS, Souhami L, Erickson BA, Winter KA, Small W Jr, Gaffney DK.  NRG Oncology/RTOG 0921: A phase 2 study of postoperative intensity-modulated radiotherapy with concurrent cisplatin and bevacizumab followed by carboplatin and paclitaxel for patients with endometrial cancer.  Cancer. 2015 Apr 6. doi: 10.1002/cncr.29337. [Epub ahead of print] PubMed PMID: 25847373.  Read More

Wong RK, Deshmukh S, Wyatt G, Sagar S, Singh AK, Sultanem K, Nguyen-Tân PF, Yom SS, Cardinale J, Yao M, Hodson I, Matthiesen CL, Suh J, Thakrar H, Pugh SL, Berk L.  Acupuncture-Like Transcutaneous Electrical Nerve Stimulation versus Pilocarpine in Treating Radiation-Induced Xerostomia: Results of RTOG 0537 Phase 3 Study.  Int J Radiat Oncol Biol Phys. 2015 Apr 1. pii: S0360-3016(15)00163-7.
doi: 10.1016/j.ijrobp.2015.01.050. [Epub ahead of print] PubMed PMID: 25841622.  Read more


Please note the following upcoming meeting and abstract submission deadline dates.

Upcoming scientific meetings

American Association for Cancer Research (AACR), Apr 18-22, 2015, Philadelphia, PA

American Association for Thoracic Surgery (AATS), Apr 25-29, 2015, Seattle, WA

American Head & Neck Society (AHNS), Apr 21–23, 2015, Boston, MA

American Society of Breast Surgeons (ASBS), Apr 29 - May 3, 2015, Orlando, FL

European Society for Radiotherapy and Oncology (ESTRO), Apr 24-28, 2015, Barcelona, Spain

Upcoming abstract submission deadline

European Society for Medical Oncology (ESMO), Sep 25-29, 2015, Vienna, Austria, meeting submission deadline Apr 28, 2015, due to Publications Committee Apr 14, 2015

International Society for Quality of Life Research (ISOQOL), Oct 21-24, 2015, Vancouver, BC, Canada, meeting submission deadline  Apr 24, 2015.

European Society of Gynaecolocial Oncology (ESGO) Oct 24-27, 2015, Nice, France, meeting submission deadline May 5, 2015, due to Publications Committee Apr 21, 2015

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